Squadron leader Ian Dornan, the pilot for the Tornado's final flight, described it as an "absolute honour and a privilege".
"It's really when I think about all the aircrew that have gone before me and all the engineers that have made it possible to put the jet in the air."
The head of the RAF, Air Chief Marshal Sir Stephen Hillier, Chief of the Air Staff, watched the jet taxi in for the last time and said it was a "hugely significant moment in the RAF's history".
"The Tornado has been the greatest part of my RAF career and so if my eyes are just a little bit glassy it's not just down to the wind that's blowing today here at Marham," he said.
The RAF chief went on to say: "The Typhoon now can fire all of the weapons that the Tornado could, and of course, the Typhoon is the next generation of combat aircraft and we've got the F-35 now has its operational capability.
"So, 37 years on its time to move on to the next generation, no matter how sad that is for so many of us."